Education
PhD, Leiden University, Biomedical Engineering (1995)
M.Sc., Sichuan University, Solid State Physics (1988)
B.S., Sichuan University, Solid State Physics (1983)
Areas of Expertise & Research Interests
Tissue engineering, nano biomaterials, drug delivery system, porous scaffolds, modification of metallic implants, interaction of biomaterials and living substance, etc.
Language(s)
English
Publications
1. Bingjun Zhang, Hongyu Li, Lei He, Zhiwei Han, Teng Zhou, Wei Zhi, Xiaobo Lu, Xiong Lu, Jie Weng*. Surface-decorated hydroxyapatite scaffold with on-demand delivery of dexamethasone and stromal cell derived factor-1 for enhanced osteogenesis. Materials Science and Engineering: C 2018, 89, 355-370.
2. Adil Elrayah, Wei Zhi, Shi Feng, Salih Al-Ezzi, He Lei, Jie Weng*. Preparation of Micro/Nano-Structure Copper-Substituted Hydroxyapatite Scaffolds with Improved Angiogenesis Capacity for Bone Regeneration. Materials 2018, 11, 1516.
3. Jingwei Zhang, Dongqin Xiao, Xu He, Feng Shi, Pinfeng Luo, Wei Zhi, Ke Duan, Jie Weng*. A novel porous bioceramic scaffold by accumulating hydroxyapatite spheres for large bone tissue engineering. III: Characterization of porous structure. Materials Science & Engineering C 2018, 89, 223-229
4. BJ Zhang, ZW Han, K Duan, YD Mu, J Weng*. Multilayered Pore-closed PLGA Microsphere Delivering OGP and BMP-2 in Sequential Release Patterns for the Facilitation of BMSCs Osteogenic Differentiation, Journal of Biomedical Materials Research. Part A 2018, 106A:95-105
5. Chenmeng Qiao, Jun Yang, Qi Shen, Yanhui Li, Yuanjie Shi, Jingli Chen, Yanqin Shen, Jie Weng*, Xin Zhang*. Traceable Nanoparticles with Dual-targeting and ROS-response for RNAi-based Immunochemotherapy of Intracranial Glioblastoma Treatment. Advanced Materials 2018, 30, 1705054
6. Bing-jun Zhang, Lei He, Zhi-wei Han, Xin-guo Li, Wei Zhi, Wei Zheng, Yan-dong Mu, Jie Weng*. Enhanced osteogenesis of multilayered poreclosed microsphere-immobilized hydroxyapatite scaffold via sequential delivery of osteogenic growth peptide and BMP-2, Journal of Materials Chemistry B 2017, 5:8238-8253
7. Chenmeng Qiao, Jun Yang, Lei Chen, Jie Weng*, Xin Zhang*. Intracellular accumulation and immunological responses of lipid modified magnetic iron nanoparticles in mouse antigen processing cells. Biomaterials Science 2017, 5, 1603-1611
8. Dongqing Xiao, Tailin Guo, Fei Yang, Gang Feng, Feng Shi, Jinyu Li, Dongwei Wang, Ke Duan, Jie Weng*, In situ formation of nanostructured calcium phosphate coatings on porous hydroxyapatite scaffolds using a hydrothermal method and the effect on mesenchymal stem cell behavior. Ceramics International 2017, 43, 1588-1596
9. Chenmeng Qiao, Jiandong Liu, Jun Yang a, Yan Li, Jie Weng*, Yiming Shao*, Xin Zhang*, Enhanced non-inflammasome mediated immune responses by mannosylated zwitterionic-based cationic liposomes for HIV DNA vaccines, Biomaterials 2016, 85:1-17
10. Jinyu Li, Wei Zhi, Taotao Xu, Feng Shi, Ke Duan, Jianxin Wang, Yangdong Mu, Jie Weng*. Ectopic osteogenesis and angiogenesis regulated by porous architecture of hydroxyapatite scaffolds with similar interconnecting structure in vivo. Regenerative Biomaterials 2016, 3:285-297.
11. Jinyu Li, Qin Wang, Wei Zhi, Jianxin Wang, Bo Feng, Shuxin Qu, Yangdong Mu, Jie Weng*. Immobilization of Salvianolic acid B-loaded chitosan microspheres distributed three-dimensionally and homogeneously on the porous surface of hydroxyapatite scaffolds. Biomedical Materials 2016, 11(5):055014
12. DQ Xiao, Z Tan, YK Fu, K Duan, XT Zheng, X Lu, J Weng*, Hydrothermal synthesis of hollow hydroxyapatite microspheres with nano-structured surface assisted by inositol hexakisphosphate, Ceramics International 40 (2014) 10183–10188
13. TL Guo, F Shi, BJ Zhang, JY Li, DW Wang, DQ Xiao, RQ Duan, W Zhi, YY Zheng, J Weng*, Modulating cellular behaviors on completely dense hydroxyapatite through biomimic pits, Ceramics International 40 (2014) 13591–13597
14. W Zhi, C Zhang, K Duan, XH Li, SX Qu, JX Wang, ZL Zhu, P Huang, T Xia, G Liao, J Weng*, A novel porous bioceramics scaffold by accumulating hydroxyapatite spherulites for large bone tissue engineering in vivo. II. Construct large volume of bone grafts, Jouranal of Biomedical Materials Research A 102A(2014)2491-2501
15. H Wang, W Zhi, X Lu, XH Li, K Duan, RQ Duan, YD Mu, J Weng*. Comparative studies on ectopic bone formation in porous hydroxyapatite scaffolds with complementary pore structures. Acta Biomater. 9(2013)8413-21
16. Zhao J, Duan K, Wang JX, Guo LY, Weng J*, Preparation of highly interconnected porous hydroxyapatite scaffolds by chitin gel-casting, Mater Sci & Eng C 31(2011)697-701
17. Peng Q, Jiang FX, Huang P, Zhou SB, Weng J*, Bao CY, Zhang C, Yu H, A novel porous bioceramics scaffold by accumulating hydroxyapatite spherulites for large bone tissue engineering in vivo. I: preparation and characterization of scaffoldl. J Biomed Mater Research 2010, 93(3), 920-929
18. Zhao J, Duan K, Zhang JW, Lu X, Weng J*, The influence of polymer concentrations on the structure and mechanical properties of porous polycaprolactone-coated hydroxyapatite scaffolds. Applied Surface Science 2010, 256, 4586-4590
19. Deng C, Yao N, Lu X, Qu SX, Feng B, Weng J*, Yang XB, Comparison of Ca/P mineralization on the surfaces of poly (ε-caprolactone) composite filled with Silane-modified nanoapatite. J. Mater. Sci. 2009, 44, 4394- 4398
20. Deng C, Weng J*, Lu X, Zhou SB, Wang JX, Qu SX, Feng B, Li XH, Preparation and in vitro bioactivity of poly(D,L-lactide) composite containing hydroxyapatite nanocrystals. Materials Science and Engineering C 2008, 28, 1304–1310;
21. Zhao J, Xiao SG, Lu X, Wang JX, Weng J*, A study on improving mechanical properties of porous HA tissue engineering scaffolds by hot isostatic pressing, Biomed Mater 1(2006)188-192
22. J Weng, M Wang, JY Chen, Plasma-sprayed calcium phosphate particles with high bioactivity and their use in bioactive scaffolds, Biomaterials 13(2002)2623-2629
23. J Weng, M Wang, Producing chitin scaffolds with controlled pore size and interconnectivity for tissue engineering, J Mater Sci Lett 20(2001)1401-1403
24. J Weng, Q Liu, JGC Wolke, X Zhang, K de Groot, Formation and characteristics of apatite layer on plasma-sprayed hydroxyapatite coatings in simulated body fluid, Biomaterials 18 (1997)1027-1035
25. J Weng, Q Liu, JGC Wolke, X Zhang, K de Groot, The role of amorphous phase in nucleating bone-like apatite on plasma-sprayed hydroxyapatite coatings in simulated body fluid, J Mater Sci Lett 16(1997)335-337
26. J Weng, X Liu, X Zhang, K de Groot, Integrity and thermal decomposition of apatite in coatings influenced by underlying titanium during plasma-spraying and post-heat-treatment, J Biomed Mater Res 30(1996)5-11
27. J Weng, X Liu, X Li, X Zhang, Intrinsic factors of apatite influencing its amorphization during plasma-spraying coating, Biomaterials 16(1995)39-44
28. J Weng, Y Cao, J Chen, X Zhang, Significance of water promoting amorphous to crystalline conversion of apatite in plasma-sprayed coatings, J Mater Sci Lett 14(1995)211-213
29. J Weng, JGC Wolke, X Zhang, K de Groot, Element-induced thermal decomposition of apatite in plasma-sprayed coatings on Ti6Al4V substrate, J Mater Sci Lett 14(1995)475-478
30. J Weng, X Liu, X Zhang, Z Ma, X Ji, Z Zyman, Further studies of the plasma-sprayed amorphous phase in hydroxyapatite coatings and its deamorphization, Biomaterials, 14(1993)578-582
Employment
(1) 1983-1992, Teaching assistant and lecturer, Institute of Materials Research, Analytical and Testing Center, Sichuan University, PR China
(2) 1992-1994, Associate professor, Institute of Materials Research, Analytical and Testing Center, Sichuan University, PR China
(3) 1996-1999, Professor, Institute of Materials Research, Analytical and Testing Center, Sichuan University, PR China
(4) 1999-2001, Research fellow, School of Mechanical and Production, Nanyang Technological University, Singapore
(5) 2001-2002, Associate Research fellow, School of Materials Science, Queen’s University, Canada
(6) 2002, Trans-century talent of Ministry of Education
(7) 2002-present, Professor, School of Materials Science and Engineering, Southwest Jiaotong University, PR China
(8) 2004, State Council Expert for Special Allowance
(9) 2008, Member of the council, Biomaterials Branch of Chinese Society for Biomedical Engineering
(10) 2012, Member of the council, Chinese Society for Biomaterials
